Fatal complication after endoscopic ultrasound-guided celiac plexus neurolysis

Fatal complication after endoscopic ultrasound-guided celiac plexus neurolysis.

A 57-year-old woman with a diagnosis of idiopathic recurrent pancreatitis and progressive epigastric pain radiating to her back was admitted to the hospital. Abdominal computed tomography (CT) showed a suspicious 3-cm pancreatic head mass involving the superior mesenteric artery (SMA) and vein. Endoscopic ultrasound (EUS) showed the suspicious pancreatic head mass with bile duct and main pancre...

End-organ ischemia as an unforeseen complication of endoscopic-ultrasound-guided celiac plexus neurolysis.

EUS-guided celiac plexus neurolysis and celiac plexus block.

Pancreatic cancer and chronic pancreatitis commonly produce pain that is difficult to control.1,2 Initial therapy with nonsteroidal anti-inflammatory agents (NSAIDs) is often inadequate and necessitates opioid administration. Although opioids effectively relieve pain, they are associated with dry mouth, constipation, nausea, vomiting, drowsiness, delirium, and may impair immune function.3,4 In ...

Pain palliation by endoscopic ultrasound-guided celiac plexus neurolysis in patients with unresectable pancreatic cancer.

BACKGROUND Endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) represents an alternative approach to pain palliation in patients with advanced pancreatic cancer. AIM to evaluate the safety and initial efficacy of EUS-CPN in patients with painful unresectable pancreatic cancer. METHODS Patients with inoperable body-tail pancreatic adenocarcinoma without prior chemotherapy and pai...

Hepatic and Splenic Infarction and Bowel Ischemia Following Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis

Endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) is a well-established intervention to palliate malignant pain. We report a patient who developed hepatic and splenic infarction and bowel ischemia following EUS-CPN. A 69-year-old man with known lung cancer and pancreatic metastasis was transferred for debilitating, significant epigastric pain for several months. The patient underw...